Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests
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Published version
Date
2021-05-24
Authors
Davidi, Dan
Fitzgerald, Susan
Glaspell, Hannah L.
Jalbert, Samantha
Klapperich, Catherine M.
Landaverde, Lena
Maheras, Stylianos
Mattoon, Stephanie E.
Britto, Vanessa M.
Nguyen, Giang T.
Version
Published version
OA Version
Citation
D. Davidi, S. Fitzgerald, H.L. Glaspell, S. Jalbert, C.M. Klapperich, L. Landaverde, S. Maheras, S.E. Mattoon, V.M. Britto, G.T. Nguyen, J.T. Platt, K. Kuhfeldt, H. Landsberg, C.W. Stuopis, J.E. Turse, D.H. Hamer, M. Springer. 2021. "Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests.." Cell Rep Methods, Volume 1, Issue 1, pp. 100005 - ?. https://doi.org/10.1016/j.crmeth.2021.100005
Abstract
Asymptomatic surveillance testing together with COVID-19-related research can lead to positive SARS-CoV-2 tests resulting not from true infections, but non-infectious, non-hazardous by-products of research (amplicons). Amplicons can be widespread and persistent in lab environments and can be difficult to distinguish for true infections. We discuss prevention and mitigation strategies.
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© 2021 The Authors. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).